The two sides immediately above the relegation zone, Stoke City and Cardiff City, meet on Wednesday at the Britannia Stadium.
Stoke were disappointing in the defeat at Everton on Saturday, a performance which suggested that the Potters are still struggling to make the transition from playing under Tony Pulis to under Mark Hughes, who has now seen his side win only one of their last 10 Premier League fixtures. However, such is the tight nature of the division; a win can see them climb as high as 11th.
Malky Mackay’s team found Arsenal much more difficult to handle than reigning champions Manchester United, as they fell to their third home reverse of the campaign. So far, they have only won once away, so defeat here will mean that Saturday’s encounter with Crystal Palace will take on great significance in the battle to stay in the top-flight.
Defender Robert Huth will be out for three weeks after undergoing surgery for a knee injury. Stoke are also likely to be without forwards Marko Arnautovic and Jonathan Walters – which would spell the end of the Irishman’s run of consecutive league starts.
Cardiff could make changes from the Arsenal defeat, with Craig Bellamy, Craig Noone and Peter Odemwingie all pushing for recalls, while Danish striker Andreas Cornelius is still waiting for his first start for the club.
See what the expert tipsters at OLBG are tipping on Stoke