Following impressive away wins in South East London, Southampton boss Ronald Koeman will be looking for his first three-point haul at home, as his side welcome Newcastle United.
Holding on to Morgan Schneiderlin will prove crucial over the season for the Saints, and so it proved last time out as his double helped see off West Ham United in what was a highly polished team performance. Transfer deadline day saw Atletico Madrid defender Toby Alderwireld arrive on loan and the free-scoring Sadio Mane join from Red Bull Salzburg, so all of a sudden, things are looking up.
While positivity has been restored on the South coast, there still seems to be a tense atmosphere around Newcastle at present, and that was not helped by the concession of a last-minute equaliser to Crystal Palace last time out.
That goal deprived them of a first win of the campaign, but the game did at least see them show some character and look more dangerous in attack. The summer signings seem still to be adapting, but youngster Rolando Aarons looks highly promising.
Alderweireld could make his debut for the hosts in place of Maya Yoshida, but Mane is expected to be on the bench. Jay Rodriguez is still sidelined by injury, and he misses out alongside Lloyd Isgrove.
Aarons is one of a number of key players missing for Newcastle, which is hardly ideal for Alan Pardew. Siem De Jong has picked up a long-term injury, while Facundo Ferreyra, Davide Santon and Ryan Taylor are all unavailable.
See what the expert tipsters at OLBG are tipping on Southampton