CAM- Ander Herrera
Herrera has yet to start a game this season, but Louis van Gaal has given an indication that he still features in his plans with two substitute appearances. He will feel he will have something to prove if he is handed his first start of the campaign.
LAM- Memphis Depay
The 21-year-old squandered a great chance to kill off the game at Villa Park, so will be desperate to open his account for the club against a side that play in a similar way to many of the Eredivisie teams he destroyed last season.
ST- Wayne Rooney
With few attacking options in the squad, van Gaal may be tempted to use Javier Hernandez. However, the Belgians will provide a stern test so the Dutchman may be more inclined to go with his talisman for the first leg.